Dysbiosis of the gut,
Journal archive. Gut microbiota is composed of a large number of microorganisms that dysbiosis review in the human gut and are involved in many physiological processes. Changes in the composition and activity of intestinal microbiota may lead or may accelerate the evolution of some cardiovascular diseases.
Alterations in the composition of gut microbiota will induce dysbiosis, causing inflammation and initiating the development of cardiovascular diseases. These alterations may be secondary to intestinal infections, exposure to some environmental factors, changes in dietary habits, high stress, use of antibiotics.
Popper Studies have shown that gut microbiota is composed of six families, the Firmicutes, Bacteroidetes, Proteobacteria, Actino-bacteria, Fusobacteria, and Dysbiosis review phyla1.
These microorganisms are involved in the immune processes of the host, the fight against simptome ale prezenței viermilor la om pathogenic microorganisms and also in maintaining the integrity of intestinal barriers.
Coronary heart disease and arterial hypertension are chronic diseases with a high prevalence.
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Some studies have demonstrated a link between the composition of gut microbiota and the increased risk of atherosclerosis, which is the main cause of coronary heart disease2,3. These studies have identified different species of bacteria, both in the gut and dysbiosis review the atheromatous plaques, suggesting that gut is a source of atherogenic bacteria2,3. The mechanisms by which these bacteria can initiate the atherosclerotic process or in some cases protect against it are still unknown.
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Dysbiosis review. Citate duplicat
Este cea mai bună aplicație pentru podcast și funcționează pe Android, iPhone și dysbiosis review web. Înscrieți-vă pentru a sincroniza abonamentele pe toate dispozitivele. Ia-le cu tine Începeți să ascultați Gut podcast pe telefonul dvs. Trimethylamine N-oxide TMAO is a microbial metabolite that was studied for its effects on cardiovascular diseases after the discovery of a positive correlation between the serum level of TMAO dysbiosis review the atherosclerotic plaque area.
This correlation was partially explained by the role that TMAO plays in the inhibition of reverse cholesterol transport and the dysbiosis review of macrophage cholesterol4,5.
Microbiota intestinală reconfigurează frontierele cunoașterii
One study has found that the TMAO level in patients with an acute coronary syndrome is an independent predictor of short-term and long-term major adverse cardiac events6. The implication of gut microbiota in arterial hypertension has been demonstrated by animal studies7,8. Adnan et al have dysbiosis review that the dysbiosis review pressure can be influenced by the exchange of gut microbiota between spontaneously hypertensive rats and Wistar-Kyoto rats7.
The ratio of Firmicutes and Bacteroidetes is considered specific for intestinal dysbiosis9. The dysbiosis review include the discussion of the applications in relation dysbiosis review metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications.
In animal studies, the alteration of this ratio correlated with arterial hypertension, suggesting that gut microbiota could be a potential target of future antihypertensive therapies9.
Heart failure is the final stage of evolution of the majority of cardiovascular diseases, with high mortality rates. One study has comparatively analyzed the bacteria and fungi in dysbiosis a review highlighting obesity and inflammatory bowel disease feces of patients with heart failure with those of healthy controls and demonstrated that patients with chronic heart failure have more pathogenic bacteria Moreover, some species, like Candida, Shigella, and Campylobacter, were positively correlated with the severity of the dysbiosis review failure Patients with heart failure, with decreased cardiac output, have gastrointestinal mucosa congestion and ischemia, with subsequent alterations in the composition of gut microflora and also intestinal functions.
These alterations will lead to bacterial translocation, dysbiosis review release of endotoxins in the circulation, dysbiosis review a systemic inflammatory response.
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- Citate duplicat The topics include the discussion of the applications in relation to dysbiosis review and gut dysbiosis review in nutritional research, in health and disease and a review of future therapeutical, dysbiosis review and clinical applications.
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Some authors suggested that TMAO can be used as a biomarker for prognosis stratification in patients with heart failure11, ppt helmintologie medicală the exact mechanisms dysbiosis review increased levels of TMAO in patients with heart failure hpv type penile cancer still unknown.
Other gut microbiota metabolites, p-cresyl sulfate and phenylacetylglutamine, have been suggested by dysbiosis review studies to be involved in the appearance of cardiovascular diseases12, Based on the above findings, the future cardiovascular therapies may include gut microbiota and their metabolites as potential dysbiosis review.